RCIS Cardiac Anatomy Study Guide

The cardiac anatomy foundations the RCIS exam builds on — chambers, valves, coronaries, and conduction.

🩺 Reviewed by our Editorial Team⏱ 4 min read🗓 Updated August 2026

Quick facts

  • 4 chambers: right atrium, right ventricle, left atrium, left ventricle.
  • 4 valves: tricuspid & mitral (AV valves), pulmonic & aortic (semilunar valves).
  • 3 major coronaries: LAD, circumflex (from the left main), and RCA.
  • Dominance is defined by which artery gives the PDA — RCA in ~85% (right dominant).
  • Conduction: SA node → AV node → bundle of His → bundle branches → Purkinje fibers.

What you will learn

Chambers & walls

The heart has four chambers. The two atria receive blood; the two ventricles pump it. The interatrial septum separates the atria (its remnant of the fetal foramen ovale is the fossa ovalis), and the thicker interventricular septum separates the ventricles.

Labeled diagram of the human heart showing the four chambers, valves, and great vessels
The chambers, valves, and great vessels of the heart. Image: Wapcaplet, CC BY-SA 3.0, via Wikimedia Commons.
ChamberReceives fromPumps to
Right atriumSVC, IVC, coronary sinusRight ventricle
Right ventricleRight atriumPulmonary artery → lungs
Left atriumFour pulmonary veinsLeft ventricle
Left ventricleLeft atriumAorta → body (thickest wall)

The four heart valves

ValveBetweenTypeLeaflets
TricuspidRA → RVAtrioventricular3
PulmonicRV → PASemilunar3
Mitral (bicuspid)LA → LVAtrioventricular2
AorticLV → aortaSemilunar3
💡 Exam tip. AV valves (tricuspid, mitral) are anchored by chordae tendineae to papillary muscles; the semilunar valves (pulmonic, aortic) create the dicrotic notch when they close. The coronary arteries arise from the aortic sinuses (sinuses of Valsalva) just above the aortic valve.

Blood flow through the heart

Follow one drop of blood:

Body → SVC/IVC → right atrium → tricuspid → right ventricle → pulmonic valve → pulmonary artery → lungs (picks up oxygen) → pulmonary veins → left atrium → mitral valve → left ventricle → aortic valve → aorta → body.

The right heart is a low-pressure pulmonary pump; the left heart is a high-pressure systemic pump — which is why the left ventricle has the thickest wall.

Coronary arteries & the wall each supplies

The left main coronary artery divides into the LAD and circumflex; the RCA arises separately. Mapping artery → wall is exactly how ECG lead groups localise an MI.

ArterySuppliesMI shows in
LAD (left anterior descending)Anterior wall, septum, apexV1–V4
CircumflexLateral wallI, aVL, V5–V6
RCA (right coronary)Inferior wall, SA/AV nodes (usually)II, III, aVF

Coronary dominance

Dominance is defined by which artery gives rise to the posterior descending artery (PDA):

The conduction system

The electrical impulse follows a fixed path:

SA node → AV node → bundle of His → right & left bundle branches → Purkinje fibers.

Exam tips

Summary & key takeaways

Practise anatomy questions

Lock in cardiac anatomy with free practice questions.

Practise Anatomy →

Frequently asked questions

Where do the coronary arteries originate?

From the aortic sinuses (sinuses of Valsalva) just above the aortic valve.

What is coronary dominance?

It is defined by which artery gives rise to the PDA — the RCA in right dominance, the circumflex in left dominance.

How many chambers and valves does the heart have?

Four chambers (two atria, two ventricles) and four valves (tricuspid, pulmonic, mitral, aortic).

Which heart valve has only two leaflets?

The mitral (bicuspid) valve; the tricuspid, pulmonic, and aortic valves each have three.

Which coronary artery supplies the inferior wall?

The right coronary artery in most people, which is why an inferior MI appears in leads II, III, and aVF.

What is the path of the cardiac conduction system?

SA node → AV node → bundle of His → right and left bundle branches → Purkinje fibers.

Sources & further reading

External links are provided for reference; always confirm current details with the official source.

RCIS Practice Test Editorial Team

Our content is written and reviewed by contributors with cardiovascular and allied-health backgrounds, grounded in standard references and the official CCI exam domains. Educational use only — not medical advice. See our editorial policy.